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The impact of MRI in current biomedical research and its role 10 years from now

发布日期:2012-05-21 16:12:52      浏览次数:

The impact of MRI in current biomedical research and its role 10 years from now
Time: 16:00~17:00, June 13
Location: Room #104, Center for Biomedical Imaging Research, Tsinghua University
Speaker: Prof. Dr. rer. nat. Jürgen Hennig (Medical Physics, Department of Radiology, University Hospital Freiburg)
 
Prof. Jürgen Hennig’s research interests are Magnetic Resonance Imaging and Spectroscopy, including Methodological Developments, Functional Neuroimaging, Molecular Imaging, Whole Body Imaging, Cardiac and Cardiovascular MR.
He is President of the European-Chinese Society for Clinical Magnetic Resonance, Past President of the International Society for Magnetic Resonance in Medicine (ISMRM), Council Member of the European Society for Magnetic Resonance in Neuropediatry, Associate Editor of the Journal of Magnetic Resonance Imaging, Associate Editor of Magnetic Resonance in Medicine and Editorial Board Member of European Radiology
 
 
Abstract:
MRI has been around for more than 40 years, but there are still intense new developments. Current intense technological and methodological developments are compressed sensing, sparse sampling, ultrahigh field MR, 13C-hyperpolarization, new concepts for spatial encoding (Inverse Imaging (InI), OVOC(MREG), PatLoc,…) and others.
In radiological MRI the focus of application is shifting from primary diagnose to the use of MR as an integrated tool for treatment monitoring in the therapeutic workflow of the patient. Functional quantitative imaging of various physiological parameters (rBF, rBV, O2, permeability, ADC,…) deliver imaging biomarkers for rational assessment of disease.
Small animal MR has developed a strong push in the ‘postgenomic’ era. Molecular biology has made tremendous progress towards understanding the elementary units of life – genes, enzymes, receptors, signaling pathways, cellular and subcellular units. Knowing the unit elements is however, not sufficient to understand their systemic integration and function. From intra- and intermolecular interactions over tissue microstructures to small structures up to the macroscopic MR scale offers the possibility to gather information over a huge range of scales. From microMR to whole body MR offers insight into morphology, anatomy, physiology, function and metabolism helping to understand the normal organism as well as disease.
MR by its inherent ability for multiparametric characterization plays a unique role in the multimodal scenario of imaging techniques used to enhance our understanding of life. With its unique ability for non-invasive examination MR will continue to play a major role in biomedical research as well as in preclinical and clinical application.