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ULTRASOUND AND PHOTOACOUSTIC MULTI-MODALITY IMAGING FOR PRECLINICAL RESEARCH

发布日期:2011-10-11 16:10:55      浏览次数:

ULTRASOUND AND PHOTOACOUSTIC MULTI-MODALITY IMAGING FOR PRECLINICAL RESEARCH
Time10:30am-11:30am, May22 (Tuesday)
Location: Room #104, Center for Biomedical Imaging Research, Tsinghua University
Speaker: Pai-Chi Li (Graduate Institute of Biomedical Electronics and Bioinformatics, Department of Electrical Engineering, National Taiwan University)
  
Abstract:
Among various molecular imaging modalities, ultrasonic imaging and photoacoustic imaging provide unique advantages and also face specific challenges. Ultrasonic molecular imaging, on one hand, is based on mechanical properties of the image object and many unique applications have been developed. With the aid of superior spatial resolution, high frequency ultrasound imaging has also evolved from clinical anatomical imaging to probing of molecular processes on small animals for pre-clinical research. Photoacoustic imaging, on the other hand, combines advantages of both optics and acoustics. Research developments in imaging physics and instrumentation have also found promising biomedical applications. In addition, microbubbles typically used in ultrasonic imaging as the contrast agent present unique mechanical properties and the associated acoustic cavitation has been exploited for therapeutic purposes. Similarly, gold nanoparticles are found to be an ideal contrast agent for photoacoustic imaging for its bioconjugation capabilities and presumed safety. The efficient light absorption of gold nanoparticles and abilities to tune their optical properties have also led to new photothermal therapy techniques. In this talk, physics, instrumentation and applications of ultrasonic and photoacoustic imaging will be reviewed. New development in combined diagnosis with therapy for both modalities will also be introduced, with a discussion on possible synergy and the technical difficulties that each modality faces, before critical clinical impact can be made.
 
 
Biography
 
Pai-Chi Li received the B.S. degree in electrical engineering from National Taiwan University, in 1987, and the M.S. and Ph.D. degrees from the University of Michigan, Ann Arbor in 1990 and 1994, respectively, both in electrical engineering: systems.
He was a research assistant with the Department of Electrical Engineering and Computer Science of the University of Michigan from 1990 to 1994. He joined Acuson Corporation, Mountain View, CA, as a member of the Technical Staff in June 1994. His work in Acuson was primarily in the areas of medical ultrasonic imaging system design for both cardiology and general imaging applications. In August 1997, he went back to the Department of Electrical Engineering at National Taiwan University, where he is currently Distinguished Professor of Department of Electrical Engineering and Founding Director of Institute of Biomedical Electronics and Bioinformatics. His current research interests include biomedical ultrasonic imaging and signal processing.
Dr. Li is IEEE Fellow, IAMBE Fellow and Associate Editor of IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. He is also Editor-in-Chief of Journal of Medical and Biological Engineering, Associate Editor of Ultrasound in Medicine and Biology and on the Editorial Board of Ultrasonic Imaging. He received the 2011 National Innovation Award, the 2009 and 2004 Distinguished Research Award, National Science Council, the 2005 Outstanding Electrical Engineering Professor Award, the Chinese Institute of Electrical Engineering, the 2004 Distinguished Research Achievement Award, National Taiwan University, the 2003 Outstanding Researcher Award, National Taiwan University, the 2002 Dr. Wu Dayou Research Award from National Science Council, the 2002 Outstanding Young Electrical Engineer Award from Chinese Institute of Electrical Engineering and the Distinguished Industrial Collaboration Award of Ministry of Education. He was also the recipient of the Distinguished Achievement Award in Electrical Engineering: Systems in 1994 for his outstanding academic achievement at the University of Michigan.