Biomechanics and Computer Simulation: Application to Aortic Dissection and Nodal Cilia Motility
发布日期：2015-03-16 15:31:35 浏览次数：次
Mechanical theories are widely employed by the studies in biology and medicine, in order to improve our understandings regarding the nature of physiological and biological systems. Realistic models of the biological subjects are usually reconstructed from experimental observation images and are analyzed by the mechanical theories via appropriate numerical methods. The results provide quantitative evaluations of the biological system and are able to reveal the mechanisms and/or predict development. In this presentation, I would like to introduce two applications of the biomechanical theories and computational simulation techniques, fluidics in aorta and molecular-driven movement in cilia. The former involves solutions of the time-variant transport equations of fluid to investigate the flow pattern and loading distributions in aortic dissection; while, the latter simulates the dynein-triggered nodal ciliary motion and evaluates the rationality of different activation patterns of the motor protein. Although these two projects target subjects at different scopes, the employed analysis methods are similar and both of them require elegant image acquisition techniques to establish realistic model and to obtain accurate results.
2011.6-至今 北京理工大学生命学院 副教授
2009.12-2011.4 英国牛津大学工程科学系 博士后研究员
2005.10-2009.9 英国牛津大学工程科学系 博士
2001.9-2005.7 上海复旦大学力学与工程科学系 学士