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郭华 研究员

郭华  特别研究员,博士生导师

2006毕业于美国杜克大学生物医学工程系,曾在Siemens公司,香港大学和美国纽约大学进行磁共振成像的研究工作。在2010年加盟清华大学前曾任美国纽约大学放射系助理教授。在核磁共振领域有超过10年的研究经验,熟悉三大磁共振系统(GESiemensPhilips)上的序列开发。目前研究兴趣主要包括两个方面。首先是磁共振物理,包括新序列设计、图像重建、对比机制研究,希望通过技术的改进来提供大信息量的高时空分辨率、多参数的定量影像或功能成像;其次是这些基本技术的临床和研究应用,特别地,感兴趣开发、优化和评估可用于慢性肝病的新的磁共振技术,进而可以提高肝病的早期诊断、治疗监测及探究背后发病的生理和病理机制。

郭华老师课题组网站http://cbir.med.tsinghua.edu.cn/ghlab/index.html

代表性文章

1. Xiaodong Ma, Zhe Zhang, Erpeng Dai, Hua Guo*. Improved Multi-shot Diffusion Imaging Using GRAPPA with a Compact Kernel. NeuroImage, 2016; doi:10.1016/j.neuroimage, in press. 

2. Erpeng Dai, Xiaodong Ma, Chun Yuan, Hua Guo*. Simultaneously Multi-Slice Accelerated Interleaved EPI DWI Using Generalized Blipped-CAIPI Acquisition and 3D K-space Reconstruction. Magnetic Resonance in Medicine, 2016; doi: 10.1002/mrm.26249, in press.

3. Qihua Yang,  Taihui Yu,  Su Yun, Hui Zhang, MS, Xiaodong Chen, Ziliang Cheng, Jinglian Zhong, Jingwen Huang, Tomoyuki Okuaki, Queenie Chan, Biling Liang*, Hua Guo*. Comparison of Multi-slice Breath-hold and 3D Respiratory Triggered T1ρ Imaging of Liver in Healthy Volunteers and Cirrhosis Patients in 3.0 T MRI: Which is More Clinically Applicable? Journal of Magnetic Resonance Imaging, 2016; doi: 10.1002/jmri.25253, in press.

4. Xiaodong Chen, Hui Zhang, Zuoquan Zhang, Zebin Luo, Qihua Yang, Ziliang Cheng, Jiaji Mao, Queenie Chan, Honggui Xu, Biling Liang, and Hua Guo*. The Value of Severe Liver Iron Overload for Assessing Heart Iron Levels in Thalassemia Major Patients. Journal of Magnetic Resonance Imaging, 2016; doi: 10.1002/jmri.25238, in press.

5. Hui Zhang, Aiqi Sun, Hongjun Li, Pairash Saiviroonporn, Ed X. Wu, Hua Guo*. Stimulated Echo Diffusion Weighted Imaging for the Liver at 3T. Magnetic Resonance in Medicine, 2016; doi: 10.1002/mrm.26128, in press.

6. Sheng Fang, Lv Li, Wenchuan Wu, Juan Wei, Dong-Hyun Kim, Chun Yuan and Hua Guo*. Multiscale Coherence Regularization Reconstruction using a Nonlocal Operator for Fast Variable-density Spiral Imaging. Magnetic Resonance Imaging, 2016; 34(7): 964–973.

7. Haitao Zhu, Binbin Nie, Hua Liu, Hua Guo, Kazuyuki Demachi, Masaki Sekino, Baoci Shan*. Quantification of Susceptibility Change at High-concentrated SPIO-labeled Target by Characteristic Phase Gradient Recognition. Magnetic Resonance Imaging, 2016; 34: 552–561.

8. Fei Wang, Kaiping Peng, Yang Bai, Rui Li, Ying Zhu, Pei Sun, Hua Guo, Chun Yuan, Pia Rotshtein, Jie Sui*. The Dorsal Anterior Cingulate Cortex Modulates Dialectical Self-thinking. Frontiers in Psychology, section Cultural Psychology, 2016; 7:152. 

9. Chuanpeng Hu, Xin Di, Simon B. Eickhoff, Mingjun Zhang, Kaiping Peng*, Hua Guo, Jie Sui*. Distinct and Common Aspects of Physical and Psychological Self-representation in the Brain: A Meta-analysis of Self-bias in Facial and Self-referential Judgements. Neuroscience & Biobehavioral Reviews, 2016; 61:197-207.

10. Hua Guo*, Xiaodong Ma, Zhe Zhang, Bida Zhang, Chun Yuan, Feng Huang. POCS-enhanced Inherent Correction of Motion-Induced Phase Errors (POCS-ICE) for High-resolution Multishot Diffusion MRI. Magnetic Resonance in Medicine, 2016; 75(1):169-80.

11. Qin Qin*, Taehoon Shin, Michael Schär, Hua Guo, Hanwei Chen, Ye Qiao. Velocity-Selective Magnetization-prepared Non-contrast-enhanced Cerebral MR Angiography at 3T: Improved Immunity to B0/B1 Inhomogeneity. Magnetic Resonance in Medicine, 2016; 75(3):1232-41.

12. Sheng Xie, Zhe Zhang, Feiyan Chang, Yishi Wang, Zhenyu Zhou, Hua Guo*. Subcortical White Matter Changes with Normal Aging Detected by Multi-shot High Resolution Diffusion Tensor Imaging. Plos One, 2016; accepted. 

13. Zhe Zhang, Feng Huang, Xiaodong Ma, Sheng Xie, Hua Guo*. Self-feeding MUSE: a Robust Method for High Resolution Diffusion Imaging using Interleaved EPI. NeuroImage, 2015; 105:552-560.

14. Xinwei Shi, Xiaodong Ma, Wenchuan Wu, Feng Huang, Chun Yuan, Hua Guo*.  Parallel Imaging and Compressed Sensing Combined Framework for Accelerating High-resolution Diffusion Tensor Imaging using Inter-image Correlation. Magnetic Resonance in Medicine, 2015; 73:1775–1785.

15. Xiaodong Chen, Zuoquan Zhang, Jinglian Zhong, Qihua Yang, Taihui Yu, Ziliang Cheng, Queenie Chan, Hua Guo, Biling Liang*. Magnetic Resonance Imaging Assessment of Excess Cardiac Iron in Thalassemia Major: When to Initiate? Journal of Magnetic Resonance Imaging, 2015; 42(3):737-45.

16. Jing Ye, Xiaobo Qu*, Hua Guo, Yunsong Liu, Di Guo, Zhong Chen. Patch-based Directional Redundant Wavelets in Compressed Sensing Parallel MRI with Radial Sampling Trajectory. Journal of Medical Imaging and Health Informatics, 2016; 6(2):387-398. 

17. Sheng Fang, Hua Guo*. Parallel variable-density spiral imaging using nonlocal total variation reconstruction. Chinese Physics B., 2014; 23(5):057401.

18. Iris Y. Zhou, Darwin S. Gao, April M. Chow, Shujuan Fan, Matthew M. Cheung, Changchun Ling, Xiaobing Liu, Peng Cao, Hua Guo, Kwan Man, Ed X. Wu*. Effect of Diffusion Time on Liver DWI: An Experimental Study of Normal and Fibrotic Livers. Magnetic Resonance in Medicine, 2014; 72:1389–1396. 

19. Zhe Liu, Zhe Zhang, Kui Ying, Chun Yuan, Hua Guo*. Improved Motion Correction in PROPELLER by using Grouped Blades as Reference. Journal of Magnetic Resonance Imaging, 2014; 39:700–707. 

20. Nan-Jie Gong, Chun-Sing Wong*, Yiu-Ching Chu, Hua Guo, Bingsheng Huang, Queenie Chan. Increasing the accuracy of volume and ADC delineation for heterogeneous tumor on diffusion-weighted MRI: correlation with PET/CT. International Journal of Radiation Oncology Biology Physics, 2013; 87(2):407-13.

21. Sheng Fang, Wen-chuan Wu,  Kui Ying, Hua Guo*, A new fast magnetic resonance imaging method based on variable-density spiral data acquisition and Bregman iterative reconstruction. Acta Physica Sinica, 2013; 62(4): 048702.

22. Xinwei Shi, Hua Guo*. Performance of Chemical Shift-based Water-fat Separation with Self-calibrated Fat Spectrum Is Sensitive to Echo Times. International Journal of Computational Biology and Drug Design, 2013; 6(3):055461.  

23. Wenbo Liu, Hua Guo, Xiaofei Du, Wenjing Zhou, Guangming Zhang, Hui Ding, Guangzhi Wang*. Cortical Vessel Imaging and Visualization for Image Guided Depth Electrode Insertion. Computerized Medical Imaging and Graphics, 2013; 37(2):123-30. 

24. Iliyana P. Atanasova,Daniel Kim, Ruth P. Lim, Pippa Storey, Hua Guo, Vivian S. Lee*. Noncontrast MR Angiography for Comprehensive Assessment of Abdominopelvic Arteries using Quadruple Inversion-Recovery Preconditioning and 3D balanced Steady-State Free Precession Imaging. Journal of Magnetic Resonance Imaging, 2011; 33(6):1430–1439. 

25. Jerry S. Cheung, Wing-Yan Au, Shau-Yin Ha, Daniel Kim, Jens H. Jensen, Iris Y. Zhou, Matthew M. Cheung, Yin Wu, Hua Guo, Pek-Lan Khong, Truman R. Brown, Gary M. Brittenham, Ed X. Wu*. Reduced Transverse Relaxation Rate (RR2) for Improved Sensitivity in Monitoring Myocardial Iron in Thalassemia. Journal of Magnetic Resonance Imaging, 2011; 33(6):1510–1516.

 

 联系方式

地址:清华大学医学院生物医学影像研究中心

邮编:100084

联系电话:+86-10-62795886

传真:+86-10-62796175

电子邮件: huaguo at mail.tsinghua.edu.cn

郭华老师课题组网站:http://cbir.med.tsinghua.edu.cn/ghlab/index.html