当前位置:  网站首页  >  科研队伍  >  专任教师

苑纯 教授

苑纯  教授、博士生导师、ISMRM院士,AHA院士, 美国华盛顿大学医学影像和生物医学系教授,清华大学影像研究中心名誉主任

苑纯教授于1982年毕业于北京师范大学物理系,1983年赴美,1988年在犹他大学取得医疗信息学博士学位,1991年开始在华盛顿大学工作,20101月起受聘于清华大学。苑纯教授利用高分辨率磁共振成像技术,首创诊断、跟踪和预测心血管动脉粥样硬化斑块的方法,并在成像序列、图像处理和诊断方法方面获得了一系列研究成果,建立、推动并引领了全球磁共振识别高危斑块的研究工作。这些研究成果不但能够识别斑块的形态,而且能够利用磁共振信号特点区分斑块的成分,从病理研究到临床诊断都有着重大的意义。迄今为止,苑纯教授已发表学术论文200余篇(其中大量论文发表在Nature Medicine、Nature Review Cardiology、Circulation、Stroke和Radiology等顶级期刊上),引用15200余次,H因子为56。会议邀请报告80余次,摘要超过300篇,参与撰写著作20部,特邀讲座145场,并于2007年出版著作Carotid Disease, the Role of Imaging in Diagnosis and Management。苑纯教授现为中组部“青年千人计划”评委,2008年至今担任国际医学磁共振学会及美国心脏学会委员,2010年至今担任AHA心血管放射学与干预委员会委员,Journal of Cardiovascular Magnetic Resonance, Journal of Cardiovascular MR 及Journal of Geriatric Cardiology 委员,《磁共振杂志》编委。目前,作为负责人共承担国际国内项目30余项,其中包括NIH(美国国家卫生研究院)项目,科技部“国家科技支撑”项目,北京市科委重大专项等。

主要科研领域与方向:

1.   心血管磁共振成像技术开发;       2. 诊断、跟踪和预测心血管动脉粥样硬化斑块的方法研究。 

文章列表:
1. Skinner MP, Yuan C, Mitsumori L, Hayes CE, Raines EW, Nelson JA, Ross R. Serial magnetic resonance imaging of experimental atherosclerosis detects lesions, fine structures, progression, and complications in vivo. Nature Medicine. 1995;1:69-73.
2. Yuan C, Mitsumori LM, Ferguson MS, Hatsukami TS. The in vivo accuracy of multispectral MR imaging for identifying lipid-rich necrotic cores and intraplaque hemorrhage in advanced human carotid plaques. Circulation, 2001; 104: 2051-2056.
3.  Yuan C, Zhang SX, Polissar NL, Echelard DE, Ortiz G, Davis, JW, Ellington E, Ferguson MS, Hatsukami TS. Identification of fibrous cap rupture with magnetic resonance imaging is highly associated with recent TIA or stroke. Circulation, 2002; 105: 181-185.
4.  Cai JM, Ferguson MS, Polissar N, Hatsukami TS, Yuan C*. Classification of Human Carotid Atherosclerotic Lesions using In Vivo Multi-Contrast MR Imaging. Circulation, 2002;106:1368-1373.
5.  Kerwin W, Hooker A, Spilker M, Vicini P, Ferguson M, Hatsukami T, Yuan C. Quantitative MRI analysis of neovasculature volume in carotid atherosclerotic plaque. Circulation, 2003;107:851-856.
6.  Saam T, Cai JM, Cai YQ, An NY, Kampschulte A, Xu D, Kerwin WS, Takaya N, Polissar NL, Hatsukami TS, Yuan C*. Carotid plaque composition differs between ethnic groups: a multi-contrast MRI study comparing mainland Chinese and American Caucasian patients. Arteriosclerosis, Thrombosis and Vascular Biology, 2005 25:611-616.
7. Cai J, Hatsukami TS, Ferguson MS, Kersin WS, Saam T, Chu B, Takaya N, Polissar NL, Yuan C*. In vivo quantitative measurement of intact fibrous cap and lipid rich necrotic core in atherosclerotic carotid plaque: a comparison of high resolution contrast enhanced MRI and histology. Circulation, 2005; 112:3437-3444.
8. Kerwin WS, O’Brien KD, Ferguson MS, Polissar N, Hatsukami TS, Yuan C. Inflammation in carotid atherosclerotic plaque: A dynamic contrast-enhanced MRI study. Radiology, 2006, 241:459-468.
9. Takaya N; Yuan C; Chu B; Saam T; Underhill H; Cai J; Tran N; Polissar NL; Isaac C; Ferguson MS; Garden GA; Cramer SC; Maravilla KR; Hashimoto B, Hatsukami TS. Association Between Carotid Plaque Characteristics and Subsequent Ischemic Cerebrovascular Events: A Prospective Assessment with Magnetic Resonance Imaging - Initial Results. Stroke, 2006; 37(3):818-823.
10. Saam T, Hatsukami TS, Takaya N, Chu B, Underhill H, Kerwin WS, Cai JM, Ferguson MS, Yuan C. The vulnerable, or high-risk, atherosclerotic plaque: noninvasive MR imaging for characterization and assessment. Radiology, 2007;244(1):64-77.
11. Underhill HR, Yarnykh VL, Hatsukami TS, Wang J, Balu N, Hayes CE, Oikawa M, Yu W, Xu C, Chu B, Wyman BT, Polissar NL, Yuan C. Carotid plaque morphology and composition: initial comparison between 1.5- and 3.0-T magnetic field strengths. Radiology. 2008: 248(2): 550-560.
12. Saam T, Underhill HR, Chu B, Takaya N, Cai J, Polissar NL, Yuan C, Hatsukami TS. Prevalence of American Heart Association type VI carotid atherosclerotic lesions identified by magnetic resonance imaging for different levels of stenosis as measured by duplex ultrasound. Journal of the American College of Cardiology, 2008; Mar 11;51(10):1014-21.
13. Underhill HR, Yuan C, Yarnykh VL. Direct quantitative comparison between cross-relaxation imaging and diffusion tensor imaging of the human brain at 3.0T. Neuroimage 2009; 47:1568-1578.
14. Underhill HR, Hatsukami TS, Fayad ZA, Fuster V, Yuan C. MRI of carotid atherosclerosis: clinical implications and future directions. Nature Reviews Cardiology 2010 Mar;7(3):165-73. Epub 2010 Jan 26.
15. Yuan C, Polissar NL, Hatsukami TS. What will noninvasive carotid atherosclerosis imaging show us about high-risk coronary plaques? J Am Coll Cardiol. 2011 Jul 19;58(4):423-5
 
联系方式
联系地址: 清华大学医学院生物医学影像研究中心
邮编:100084
联系电话:010-6279175
传真:010-62796175
Email: cyuan@tsinghua.edu.cn